Topera Medical’s FDA-Cleared RhythmView System Featured in 16 Presentations at Heart Rhythm Society 2012 Scientific Sessions

RhythmView Used to Reveal Sources that Sustain Complex Atrial and Ventricular Arrhythmias

SAN DIEGO--(BUSINESS WIRE)--Topera Medical today announced that its FDA-cleared RhythmView™ 3D mapping and diagnostic system will be featured in 16 scientific presentations at the 33^rd Annual Scientific Sessions of the Heart Rhythm Society (HRS), May 9-12 in Boston. The presentations will provide clinicians with additional information about the electrical source of atrial arrhythmias and will also introduce information on sources that drive ventricular arrhythmias.

"RhythmView's contribution to these presentations speaks to the expanding interest in applying this 3D mapping platform in clinical practice"

"RhythmView's contribution to these presentations speaks to the expanding interest in applying this 3D mapping platform in clinical practice," said Edward Kerslake, Topera Medical's Chief Executive Officer. "RhythmView's ability to resolve rotors in ventricular arrhythmias will be reported for the first time. This represents an interesting application for RhythmView beyond the atrial rotor mapping previously reported, and is a logical extension of our platform technology. As we prepare for the commercial launch in early 2013, we are pleased to see Topera's technology taking a lead role in transforming the way electrophysiology procedures are performed."

Schedule of scientific presentations (All times are Eastern time, with events to be held at the Boston Convention Center):

Wednesday, May 9

1:45 p.m. AF Summit at the World Trade Center

Mapping Based Catheter Ablation of Rotors in Long Standing Persistent AF.

3:00 p.m. in room 160A

AB02-03 - Targeted Ablation at Sources Alone (Focal Impulse and Rotor Modulation, FIRM) Acutely Terminates or Slows Human Atrial Fibrillation.

5:45 p.m. in the Exhibit Hall

PO1-105 - Correlation of Electrogram Characteristics and Localized Sources for Human AF.

PO1-126 -Ventricular Fibrillation Rotors Are Located in Both Ventricles in Patients with and without Structural Heart Disease.

Thursday, May 10

9:30 a.m. in the Exhibit Hall

PO2-52 - Determinants of the Number of Localized Sources for Human Atrial Fibrillation.

PO2-62 - Rotors and Focal Impulses: Mechanisms to Explain Atrial Fibrillation Initiation Remote from Triggers.

PO2-116 - Physiologically-Guided Ablation Reduces Need for Conventional Ablation of Atrial Fibrillation.

PO2-149 - Percutaneous Detection of Electrical Rotors That Drive Human Ventricular Fibrillation.

1:30 p.m. in room 253A

AB14-01 - Human Atrial Fibrillation Is Initiated by Rotors or Repetitive Focal beats that are Consistent for Multiple Triggers.

2:00 p.m. in the Exhibit Hall

PO3-61 - Identification of Localized Sources for Human Atrial Fibrillation from the Surface Electrocardiogram.

PO3-150 - Increased Global Surface ECG Phase Correlation Predicts Human Ventricular Fibrillation Rotors.

2:45 p.m. in room 210C

AB03 - Success of Focal Impulse and Rotor Modulation (FIRM) for Human Atrial Fibrillation Reflects the Adequacy of Basket Recordings.

3:45 p.m. in the Exhibit Hall

MPO2-04 - Rotors and Focal Beat Sources for Human Atrial Fibrillation Migrate Within Limited Constrained Areas.

Friday, May 11

12:30 p.m. in room 158

Classifying Fractionated Electrograms in Human Atrial Fibrillation Using Monophasic Action Potentials and Activation Mapping: Evidence for Localized Drivers, Rate Acceleration, and Nonlocal Signal Etiologies.

2:00 p.m. in room 160A

AB02-03 - Targeted Ablation at Sources Alone (Focal Impulse and Rotor Modulation, FIRM) Acutely Terminates or Slows Human Atrial Fibrillation.

2:30 p.m. in room 253A

AB35-05 - Sustaining Rotors and Focal Beats for Human Atrial Fibrillation Are Unrelated to Sites of Fractionated Electrograms.

For a complete list of all presentations featuring RhythmView to be presented at HRS, please visit www.toperamedical.com.

About Topera Medical (www.toperamedical.com)

Topera Medical (Topera, Inc.) has developed the RhythmView™, 3D analysis and mapping system to assist electrophysiologists in the identification of the electrical source of complex cardiac arrhythmias. The RhythmView system, including the RhythmView console and FIRMap™ catheter, is designed to improve patient outcomes by enabling electrophysiologists to view a dynamic representation of the electrical activity of the heart, supporting the diagnosis of and treatment planning for a variety of arrhythmias including atrial flutter, atrial tachycardia, ventricular tachycardia, and atrial fibrillation (AF).